Prenatal restraint stress generates two distinct behavioral and neurochemical profiles in male and female rats.

Prenatal Restraint Stress (PRS) in rats is a validated model of early stress resulting in permanent behavioral and neurobiological outcomes. Although sexual dimorphism in the effects of PRS has been hypothesized for more than 30 years, few studies in this long period have directly addressed the issu...

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Main Authors: Anna Rita Zuena, Jerome Mairesse, Paola Casolini, Carlo Cinque, Giovanni Sebastiano Alemà, Sara Morley-Fletcher, Valentina Chiodi, Luigi Giusto Spagnoli, Roberto Gradini, Assia Catalani, Ferdinando Nicoletti, Stefania Maccari
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2366064?pdf=render