An IL-13 promoter polymorphism associated with liver fibrosis in patients with Schistosoma japonicum.

The aim of this study was to determine whether two polymorphisms in the gene encoding IL13 previously associated with Schistosoma hematobium (S. hematobium) and S. mansoni infection are associated with S. japonicum infection. Single nucleotide polymorphisms (SNPs) rs1800925 (IL13/-1112C>T) and rs...

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Main Authors: Xin Long, Qian Chen, Jianping Zhao, Nicholas Rafaels, Priyanka Mathias, Huifang Liang, Joseph Potee, Monica Campbell, Bixiang Zhang, Li Gao, Steve N Georas, Donata Vercelli, Terri H Beaty, Ingo Ruczinski, Rasika Mathias, Kathleen C Barnes, Xiaoping Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4530950?pdf=render