Influenza Virus-Induced Robust Expression of SOCS3 Contributes to Excessive Production of IL-6

Influenza A virus (IAV) remains a major public health threat in the world, as indicated by the severe pneumonia caused by its infection annually. Interleukin-6 (IL-6) involved excessive inflammatory response to IAV infection profoundly contributes to the virus pathogenesis. However, the precise mech...

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Bibliographic Details
Main Authors: Shasha Liu, Ruoxiang Yan, Biao Chen, Qidong Pan, Yuhai Chen, Jinxuan Hong, Lianfeng Zhang, Wenjun Liu, Song Wang, Ji-Long Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01843/full