PHF6 Expression Levels Impact Human Hematopoietic Stem Cell Differentiation

PHF6 Expression Levels Impact Human Hematopoietic Stem Cell Differentiation

Transcriptional control of hematopoiesis involves complex regulatory networks and functional perturbations in one of these components often results in malignancies. Loss-of-function mutations in PHF6, encoding a presumed epigenetic regulator, have been primarily described in T cell acute lymphoblast...

Full description

Bibliographic Details
Main Authors: Siebe Loontiens, Anne-Catherine Dolens, Steven Strubbe, Inge Van de Walle, Finola E. Moore, Lisa Depestel, Suzanne Vanhauwaert, Filip Matthijssens, David M. Langenau, Frank Speleman, Pieter Van Vlierberghe, Kaat Durinck, Tom Taghon
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
hematopoiesis
PHF6
NOTCH
zebrafish
T cell development
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2020.599472/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2020.599472/full

Similar Items