Pyramidal cells accumulate chloride at seizure onset

Seizures are thought to originate from a failure of inhibition to quell hyperactive neural circuits, but the nature of this failure remains unknown. Here we combine high-speed two-photon imaging with electrophysiological recordings to directly evaluate the interaction between populations of interneu...

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Bibliographic Details
Main Authors: Kyle P. Lillis, Mark A. Kramer, Jerome Mertz, Kevin J. Staley, John A. White
Format: Article
Language:English
Published: Elsevier 2012-09-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996112002021