Recent advances toward a molecular mechanism of efflux pump inhibition

Multi-drug resistance (MDR) in Gram-negative pathogens, such as the Enterobacteriaceae and Pseudomonas aeruginosa, poses a significant threat to our ability to effectively treat infections caused by these organisms. A major component in the development of the MDR phenotype in Gram-negative bacteria...

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Bibliographic Details
Main Authors: Timothy J Opperman, Son T Nguyen
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-05-01
Series:Frontiers in Microbiology
Subjects:
EPI
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00421/full