Dynamics of cerebrospinal fluid levels of matrix metalloproteinases in human traumatic brain injury

Abstract Matrix metalloproteinases (MMPs) are extracellular enzymes involved in the degradation of extracellular matrix (ECM) proteins. Increased expression of MMPs have been described in traumatic brain injury (TBI) and may contribute to additional tissue injury and blood–brain barrier damage. The...

Full description

Bibliographic Details
Main Authors: Karolina Minta, Gunnar Brinkmalm, Faiez Al Nimer, Eric P. Thelin, Fredrik Piehl, Mats Tullberg, Anna Jeppsson, Erik Portelius, Henrik Zetterberg, Kaj Blennow, Ulf Andreasson
Format: Article
Language:English
Published: Nature Publishing Group 2020-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-75233-z