Effect of Cetuximab-Conjugated Gold Nanoparticles on the Cytotoxicity and Phenotypic Evolution of Colorectal Cancer Cells

Effect of Cetuximab-Conjugated Gold Nanoparticles on the Cytotoxicity and Phenotypic Evolution of Colorectal Cancer Cells

Epidermal growth factor receptor (EGFR) is estimated to be overexpressed in 60~80% of colorectal cancer (CRC), which is associated with a poor prognosis. Anti-EGFR targeted monoclonal antibodies (cetuximab and panitumumab) have played an important role in the treatment of metastatic CRC. However, th...

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Bibliographic Details
Main Authors: Ralph El Hallal, Nana Lyu, Yuling Wang
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Molecules
Subjects:
epidermal growth factor receptor
colorectal cancer
cetuximab
cytotoxicity
gold nanoparticles
surface-enhanced Raman scattering/spectroscopy
Online Access:https://www.mdpi.com/1420-3049/26/3/567

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https://www.mdpi.com/1420-3049/26/3/567

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