Baicalin Inhibits Hypoxia-Induced Pulmonary Artery Smooth Muscle Cell Proliferation via the AKT/HIF-1α/p27-Associated Pathway

Baicalin Inhibits Hypoxia-Induced Pulmonary Artery Smooth Muscle Cell Proliferation via the AKT/HIF-1α/p27-Associated Pathway

Baicalin, a flavonoid compound purified from the dry roots of Scutellaria baicalensis Georgi, has been shown to possess various pharmacological actions. Previous studies have revealed that baicalin inhibits the growth of cancer cells through the induction of apoptosis. Pulmonary arterial hypertensi...

Full description

Bibliographic Details
Main Authors: Lin Zhang, Zhichen Pu, Junsong Wang, Zhifeng Zhang, Dongmei Hu, Junjie Wang
Format: Article
Language:English
Published: MDPI AG 2014-05-01
Series:International Journal of Molecular Sciences
Subjects:
baicalin
pulmonary hypertension
pulmonary artery smooth muscle cells
proliferation
Online Access:http://www.mdpi.com/1422-0067/15/5/8153

Internet

http://www.mdpi.com/1422-0067/15/5/8153

Similar Items