Increased Plasmodium falciparum Parasitemia in Non-splenectomized Saimiri sciureus Monkeys Treated with Clodronate Liposomes

Increased Plasmodium falciparum Parasitemia in Non-splenectomized Saimiri sciureus Monkeys Treated with Clodronate Liposomes

A major constraint in the study of Plasmodium falciparum malaria, including vaccine development, lies on the parasite's strict human host specificity and therefore the shortage of animal experimental models able to harbor human plasmodia. The best experimental models are neo-tropical primates o...

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Bibliographic Details
Main Authors: Janaiara A. Cunha, Leonardo J. M. Carvalho, Cesare Bianco-Junior, Márcia C. R. Andrade, Lilian R. Pratt-Riccio, Evelyn K. P. Riccio, Marcelo Pelajo-Machado, Igor J. da Silva, Pierre Druilhe, Cláudio Tadeu Daniel-Ribeiro
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
malaria
Plasmodium falciparum
Saimiri sciureus
clodronate liposomes
macrophages
spleen
Online Access:http://journal.frontiersin.org/article/10.3389/fcimb.2017.00408/full

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http://journal.frontiersin.org/article/10.3389/fcimb.2017.00408/full

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