Intravital FRET imaging of tumor cell viability and mitosis during chemotherapy.

Taxanes, such as docetaxel, are microtubule-targeting chemotherapeutics that have been successfully used in the treatment of cancer. Based on data obtained from cell cultures, it is believed that taxanes induce tumor cell death by specifically perturbing mitotic progression. Here, we report on data...

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Bibliographic Details
Main Authors: Aniek Janssen, Evelyne Beerling, René Medema, Jacco van Rheenen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3654962?pdf=render