In Silico Docking, Molecular Dynamics and Binding Energy Insights into the Bolinaquinone-Clathrin Terminal Domain Binding Site

Clathrin-mediated endocytosis (CME) is a process that regulates selective internalization of important cellular cargo using clathrin-coated vesicles. Perturbation of this process has been linked to many diseases including cancer and neurodegenerative conditions. Chemical proteomics identified the ma...

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Bibliographic Details
Main Authors: Mohammed K. Abdel-Hamid, Adam McCluskey
Format: Article
Language:English
Published: MDPI AG 2014-05-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/19/5/6609