Evaluation of Whole-Exome Enrichment Solutions: Lessons from the High-End of the Short-Read Sequencing Scale

Evaluation of Whole-Exome Enrichment Solutions: Lessons from the High-End of the Short-Read Sequencing Scale

Whole-exome sequencing has become a popular technique in research and clinical settings, assisting in disease diagnosis and increasing the understanding of disease pathogenesis. In this study, we aimed to compare common enrichment capture solutions available in the market. Peripheral blood-purified...

Full description

Bibliographic Details
Main Authors: Ana Díaz-de Usera, Jose M. Lorenzo-Salazar, Luis A. Rubio-Rodríguez, Adrián Muñoz-Barrera, Beatriz Guillen-Guio, Itahisa Marcelino-Rodríguez, Víctor García-Olivares, Alejandro Mendoza-Alvarez, Almudena Corrales, Antonio Íñigo-Campos, Rafaela González-Montelongo, Carlos Flores
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Journal of Clinical Medicine
Subjects:
next-generation sequencing
whole-exome sequencing
target coverage
duplicate reads
genetic variation
Online Access:https://www.mdpi.com/2077-0383/9/11/3656

Internet

https://www.mdpi.com/2077-0383/9/11/3656

Similar Items