Exploring the dominant role of Cav1 channels in signalling to the nucleus

Exploring the dominant role of Cav1 channels in signalling to the nucleus

Calcium is important in controlling nuclear gene expression through the activation of multiple signal-transduction pathways in neurons. Compared with other voltage-gated calcium channels, CaV1 channels demonstrate a considerable advantage in signalling to the nucleus. In this review, we summarize th...

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Bibliographic Details
Main Authors: Huan Ma, Samuel Cohen, Boxing Li, Richard W. Tsien
Format: Article
Language:English
Published: Portland Press, Biochemical Society 2012-12-01
Series:Bioscience Reports
Subjects:
calcium channel
Ca2+/calmodulin-dependent protein kinase II (CaMKII)
cAMP response element-binding (CREB)
endoplasmic reticulum (ER)
gene transcription
mitochondrion
Online Access:http://www.bioscirep.org/bsr/033/e009/bsr033e009.htm

Internet

http://www.bioscirep.org/bsr/033/e009/bsr033e009.htm

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