Immune Complexes Indirectly Suppress the Generation of Th17 Responses In Vivo.

The precise context in which the innate immune system is activated plays a pivotal role in the subsequent instruction of CD4+ T helper (Th) cell responses. Th1 responses are downregulated when antigen is encountered in the presence of antigen-IgG immune complexes. To assess if Th17 responses to anti...

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Bibliographic Details
Main Authors: Ceren Ciraci, John R Janczy, Nidhi Jain, Stefanie Haasken, Cyntia Pecli E Silva, Claudia F Benjamim, Jeffrey J Sadler, Alicia K Olivier, Yoichiro Iwakura, Dmitry M Shayakhmetov, Fayyaz S Sutterwala, Suzanne L Cassel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4792482?pdf=render