GMP-compliant production of [68Ga]Ga-NeoB for positron emission tomography imaging of patients with gastrointestinal stromal tumor

GMP-compliant production of [68Ga]Ga-NeoB for positron emission tomography imaging of patients with gastrointestinal stromal tumor

Abstract Background [68Ga]Ga-NeoB is a novel DOTA-coupled Gastrin Releasing Peptide Receptor (GRPR) antagonist with high affinity for GRPR and good in vivo stability. This study aimed at (1) the translation of preclinical results to the clinics and establish the preparation of [68Ga]Ga-NeoB using a...

Full description

Bibliographic Details
Main Authors: Marc Pretze, Laura Reffert, Steffen Diehl, Stefan O. Schönberg, Carmen Wängler, Peter Hohenberger, Björn Wängler
Format: Article
Language:English
Published: SpringerOpen 2021-07-01
Series:EJNMMI Radiopharmacy and Chemistry
Subjects:
[68Ga]Ga-NeoB
GRPR
GMP
PET/CT
Metastatic GIST
Online Access:https://doi.org/10.1186/s41181-021-00137-w

Internet

https://doi.org/10.1186/s41181-021-00137-w

Similar Items