Modulation of caspase activity regulates skeletal muscle regeneration and function in response to vasopressin and tumor necrosis factor.

Muscle homeostasis involves de novo myogenesis, as observed in conditions of acute or chronic muscle damage. Tumor Necrosis Factor (TNF) triggers skeletal muscle wasting in several pathological conditions and inhibits muscle regeneration. We show that intramuscular treatment with the myogenic factor...

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Bibliographic Details
Main Authors: Viviana Moresi, Gisela Garcia-Alvarez, Alessandro Pristerà, Emanuele Rizzuto, Maria C Albertini, Marco Rocchi, Giovanna Marazzi, David Sassoon, Sergio Adamo, Dario Coletti
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2680623?pdf=render