Combination of a six microRNA expression profile with four clinicopathological factors for response prediction of systemic treatment in patients with advanced colorectal cancer.

Combination of a six microRNA expression profile with four clinicopathological factors for response prediction of systemic treatment in patients with advanced colorectal cancer.

BACKGROUND:First line chemotherapy is effective in 75 to 80% of patients with metastatic colorectal cancer (mCRC). We studied whether microRNA (miR) expression profiles can predict treatment outcome for first line fluoropyrimidine containing systemic therapy in patients with mCRC. METHODS:MiR expres...

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Bibliographic Details
Main Authors: Maarten Neerincx, Dennis Poel, Daoud L S Sie, Nicole C T van Grieken, Ram C Shankaraiah, Floor S W van der Wolf-de Lijster, Jan-Hein T M van Waesberghe, Jan-Dirk Burggraaf, Paul P Eijk, Cornelis Verhoef, Bauke Ylstra, Gerrit A Meijer, Mark A van de Wiel, Tineke E Buffart, Henk M W Verheul
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6075783?pdf=render

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http://europepmc.org/articles/PMC6075783?pdf=render

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