Reverse Genetic Strategies in Caenorhabditis elegans: Towards Controlled Manipulation of the Genome

Caenorhabditis elegans has a complete annotated genome sequence that is augmented by increasing quantities of data from high-throughput postgenomic analyses. This has led to an increasing need to identify the biological functions of specific genes using reverse genetics, i.e., moving from gene to ph...

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Bibliographic Details
Main Authors: Howard A. Baylis, Rafael P. Vázquez-Manrique
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1100/tsw.2011.126