Replacement of asymmetric synaptic profiles in the molecular layer of dentate gyrus following cycloheximide in the pilocarpine model in rats.

Replacement of asymmetric synaptic profiles in the molecular layer of dentate gyrus following cycloheximide in the pilocarpine model in rats.

Mossy fiber sprouting is among the best-studied forms of post-lesional synaptic plasticity and is regarded by many as contributory to seizures in both humans and animal models of epilepsy. It is not known whether mossy fiber sprouting increases the number of synapses in the molecular layer or merely...

Full description

Bibliographic Details
Main Authors: Simone eBittencourt, Luciene eCovolan, Clement eHamani, Beatriz Monteiro Longo, Flavio Paulo Faria, Edna eFreymuller, Ole Petter Ottersen, Luiz E Mello
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-11-01
Series:Frontiers in Psychiatry
Subjects:
Cycloheximide
Status Epilepticus
synaptic plasticity
mossy fiber sprouting
asymmetric synaptic profiles
Online Access:http://journal.frontiersin.org/Journal/10.3389/fpsyt.2015.00157/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fpsyt.2015.00157/full

Similar Items