Inhibition of receptor tyrosine kinase signalling by small molecule agonist of T-cell protein tyrosine phosphatase

<p>Abstract</p> <p>Background</p> <p>T-cell protein tyrosine phosphatase (TCPTP/TC45) is a ubiquitously expressed intra-cellular non-receptor protein tyrosine phosphatase involved in the negative regulation of several cancer relevant cellular signalling pathways. We hav...

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Bibliographic Details
Main Authors: Tähtinen Siri, Kohonen Pekka, Sahlberg Niko, Marttila Heidi, Mattila Elina, Halonen Pasi, Perälä Merja, Ivaska Johanna
Format: Article
Language:English
Published: BMC 2010-01-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/10/7