Site-Directed Mutation, Cloning and Expression of Streptokinase for Producing a New Suitable Molecule for PEGylation

Abstract Background: Streptokinase is one of the most common and cost effective fibrinolytic drugs for treatment of heart attacks and vein thrombosis. Unlike many advantages over other thrombolytic drugs, administration of streptokinase can produce some complications such as immunologic reactions,...

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Bibliographic Details
Main Authors: Somayeh Bagheri, Hossein Maghsoudi, Fatemeh Motevalli, Farahnaz Khoshdel Nezamiha, Seyed Mehdi Hasanzadeh, Reza Arabi Mianroodi
Format: Article
Language:fas
Published: Arak Medical University 2016-06-01
Series:Majallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk
Subjects:
Online Access:http://amuj.arakmu.ac.ir/article-1-4189-en.pdf