Association of Body Mass Index with DNA Methylation and Gene Expression in Blood Cells and Relations to Cardiometabolic Disease: A Mendelian Randomization Approach.
<h4>Background</h4>The link between DNA methylation, obesity, and adiposity-related diseases in the general population remains uncertain.<h4>Methods and findings</h4>We conducted an association study of body mass index (BMI) and differential methylation for over 400,000 CpGs...
Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2017-01-01
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Series: | PLoS Medicine |
Online Access: | https://doi.org/10.1371/journal.pmed.1002215 |