Functions of Muscarinic Receptor Subtypes in Gastrointestinal Smooth Muscle: A Review of Studies with Receptor-Knockout Mice

Functions of Muscarinic Receptor Subtypes in Gastrointestinal Smooth Muscle: A Review of Studies with Receptor-Knockout Mice

Parasympathetic signalling via muscarinic acetylcholine receptors (mAChRs) regulates gastrointestinal smooth muscle function. In most instances, the mAChR population in smooth muscle consists mainly of M<sub>2</sub> and M<sub>3</sub> subtypes in a roughly 80% to 20% mixture....

Full description

Bibliographic Details
Main Authors: Yasuyuki Tanahashi, Seiichi Komori, Hayato Matsuyama, Takio Kitazawa, Toshihiro Unno
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Molecular Sciences
Subjects:
muscarinic receptor subtypes
knockout mouse
smooth muscle
gastrointestinal tract
non-selective cationic channels
signal transduction pathways
Online Access:https://www.mdpi.com/1422-0067/22/2/926

Internet

https://www.mdpi.com/1422-0067/22/2/926

Similar Items