The Role of Merkel Cell Polyomavirus and Other Human Polyomaviruses in Emerging Hallmarks of Cancer

Polyomaviruses are non-enveloped, dsDNA viruses that are common in mammals, including humans. All polyomaviruses encode the large T-antigen and small t-antigen proteins that share conserved functional domains, comprising binding motifs for the tumor suppressors pRb and p53, and for protein phosphata...

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Bibliographic Details
Main Authors: Ugo Moens, Kashif Rasheed, Ibrahim Abdulsalam, Baldur Sveinbjørnsson
Format: Article
Language:English
Published: MDPI AG 2015-04-01
Series:Viruses
Subjects:
Online Access:http://www.mdpi.com/1999-4915/7/4/1871