B cells promote tumor progression via STAT3 regulated-angiogenesis.

The role of B cells in cancer and the underlying mechanisms remain to be further explored. Here, we show that tumor-associated B cells with activated STAT3 contribute to tumor development by promoting tumor angiogenesis. B cells with or without Stat3 have opposite effects on tumor growth and tumor a...

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Bibliographic Details
Main Authors: Chunmei Yang, Heehyoung Lee, Sumanta Pal, Veronica Jove, Jiehui Deng, Wang Zhang, Dave S B Hoon, Mark Wakabayashi, Stephen Forman, Hua Yu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3667024?pdf=render