Nonclonal Chromosome Aberrations and Genome Chaos in Somatic and Germ Cells from Patients and Survivors of Hodgkin Lymphoma

Nonclonal Chromosome Aberrations and Genome Chaos in Somatic and Germ Cells from Patients and Survivors of Hodgkin Lymphoma

Anticancer regimens for Hodgkin lymphoma (HL) patients include highly genotoxic drugs that have been very successful in killing tumor cells and providing a 90% disease-free survival at five years. However, some of these treatments do not have a specific cell target, damaging both cancerous and norma...

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Bibliographic Details
Main Authors: Sara Frias, Sandra Ramos, Consuelo Salas, Bertha Molina, Silvia Sánchez, Roberto Rivera-Luna
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Genes
Subjects:
chromosome instability (CIN)
chromoplexy
genome chaos
chromosomal heterogeneity
karyotype heterogeneity
nonclonal chromosome aberration (NCCA)
second cancer
virus reactivation
Online Access:http://www.mdpi.com/2073-4425/10/1/37

Internet

http://www.mdpi.com/2073-4425/10/1/37

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