Roles of NOD1 (NLRC1) and NOD2 (NLRC2) in innate immunity and inflammatory diseases

Roles of NOD1 (NLRC1) and NOD2 (NLRC2) in innate immunity and inflammatory diseases

NOD1 {nucleotide-binding oligomerization domain 1; NLRC [NOD-LRR (leucine-rich repeat) family with CARD (caspase recruitment domain) 1]} and NOD2 (NLRC2) are among the most prominent members of the NLR (NOD-LRR) family –proteins that contain nucleotide-binding NACHT domains and receptor-l...

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Bibliographic Details
Main Authors: Ricardo G. Correa, Snezana Milutinovic, John C. Reed
Format: Article
Language:English
Published: Portland Press, Biochemical Society 2012-10-01
Series:Bioscience Reports
Subjects:
inflammation
nuclear factor-κB (NF-κB)
nucleotide-binding oligomerization domain 1 (NOD1)
nucleotide-binding oligomerization domain (NOD) leucine-rich repeat (NLR)
nucleotide-binding oligomerization domain 2 (NOD2)
Online Access:http://www.bioscirep.org/bsr/032/0597/bsr0320597.htm

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