Impaired macrophage and satellite cell infiltration occurs in a muscle-specific fashion following injury in diabetic skeletal muscle.

Impaired macrophage and satellite cell infiltration occurs in a muscle-specific fashion following injury in diabetic skeletal muscle.

Systemic elevations in PAI-1 suppress the fibrinolytic pathway leading to poor collagen remodelling and delayed regeneration of tibialis anterior (TA) muscles in type-1 diabetic Akita mice. However, how impaired collagen remodelling was specifically attenuating regeneration in Akita mice remained un...

Full description

Bibliographic Details
Main Authors: Matthew P Krause, Dhuha Al-Sajee, Donna M D'Souza, Irena A Rebalka, Jasmin Moradi, Michael C Riddell, Thomas J Hawke
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3741394?pdf=render

Internet

http://europepmc.org/articles/PMC3741394?pdf=render

Similar Items