Tolcapone addition improves Parkinson’s disease associated nonmotor symptoms

Background: Addition of catechol-O-methyltransferase inhibitors to a conventional levodopa/dopadecarboxylase inhibitor regimen improves motor symptoms in patients with Parkinson’s disease. Optimizing dopamine substitution is also beneficial for nonmotor features. Objectives: To investigate the effic...

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Bibliographic Details
Main Author: Thomas Müller
Format: Article
Language:English
Published: SAGE Publishing 2014-03-01
Series:Therapeutic Advances in Neurological Disorders
Online Access:https://doi.org/10.1177/1756285613512392