PGC-1alpha inhibits oleic acid induced proliferation and migration of rat vascular smooth muscle cells.

PGC-1alpha inhibits oleic acid induced proliferation and migration of rat vascular smooth muscle cells.

Oleic acid (OA) stimulates vascular smooth muscle cell (VSMC) proliferation and migration. The precise mechanism is still unclear. We sought to investigate the effects of peroxisome proliferator-activated receptor gamma (PPARgamma) coactivator-1 alpha (PGC-1alpha) on OA-induced VSMC proliferation an...

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Bibliographic Details
Main Authors: Yan Zhang, Chang Liu, Lingyun Zhu, Xiaohong Jiang, Xi Chen, Xiaoqiang Qi, Xiangying Liang, Sonia Jin, Peixiang Zhang, Qingguo Li, Dongjin Wang, Xiaofeng Liu, Ke Zeng, Junfeng Zhang, Yang Xiang, Chen-Yu Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2043491?pdf=render

Internet

http://europepmc.org/articles/PMC2043491?pdf=render

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