Lipoic acid, but not tempol, preserves vascular compliance and decreases medial calcification in a model of elastocalcinosis

Vascular calcification decreases compliance and increases morbidity. Mechanisms of this process are unclear. The role of oxidative stress and effects of antioxidants have been poorly explored. We investigated effects of the antioxidants lipoic acid (LA) and tempol in a model of atherosclerosis assoc...

Full description

Bibliographic Details
Main Authors: E. Bassi, M. Liberman, M.K. Martinatti, L.A. Bortolotto, F.R.M. Laurindo
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2014-02-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2014000200119&lng=en&tlng=en