DltX of Bacillus thuringiensis Is Essential for D-Alanylation of Teichoic Acids and Resistance to Antimicrobial Response in Insects

DltX of Bacillus thuringiensis Is Essential for D-Alanylation of Teichoic Acids and Resistance to Antimicrobial Response in Insects

The dlt operon of Gram-positive bacteria is required for the incorporation of D-alanine esters into cell wall-associated teichoic acids (TAs). Addition of D-alanine to TAs reduces the negative charge of the cell envelope thereby preventing cationic antimicrobial peptides (CAMPs) from reaching their...

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Bibliographic Details
Main Authors: Rita Kamar, Agnès Réjasse, Isabelle Jéhanno, Zaynoun Attieh, Pascal Courtin, Marie-Pierre Chapot-Chartier, Christina Nielsen-Leroux, Didier Lereclus, Laure el Chamy, Mireille Kallassy, Vincent Sanchis-Borja
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-08-01
Series:Frontiers in Microbiology
Subjects:
B. thuringiensis
dltX
antimicrobial peptides
virulence
D-alanylation
insects
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2017.01437/full

Internet

http://journal.frontiersin.org/article/10.3389/fmicb.2017.01437/full

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