Hepatic BRD4 Is Upregulated in Liver Fibrosis of Various Etiologies and Positively Correlated to Fibrotic Severity

Hepatic BRD4 Is Upregulated in Liver Fibrosis of Various Etiologies and Positively Correlated to Fibrotic Severity

Bromodomain-containing protein 4 (BRD4) has been implicated to play a regulatory role in fibrogenic gene expression in animal models of liver fibrosis. The potential role of BRD4 in liver fibrosis in humans remains unclear. We sought to investigate the expression and cellular localization of BRD4 in...

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Bibliographic Details
Main Authors: Cichun Wu, Da Cheng, Yanghui Peng, Ying Li, Chunyan Fu, Ying Wang, Lei Fu, Shifang Peng, Xin Ni
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Medicine
Subjects:
liver fibrosis
BRD4
CXCL6
HBV
human samples
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2021.683506/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2021.683506/full

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