Anti-VEGF Signalling Mechanism in HUVECs by Melatonin, Serotonin, Hydroxytyrosol and Other Bioactive Compounds

Angiogenesis drives evolution and destabilisation of atherosclerotic plaques and the growth and expansion of tumour cells. Vascular endothelial growth factor (VEGF) is the main endogenous pro-angiogenic factor in humans. The aim was to provide insight into the anti-VEGF activity of bioactive compoun...

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Bibliographic Details
Main Authors: Ana B. Cerezo, María Labrador, Andrés Gutiérrez, Ruth Hornedo-Ortega, Ana M. Troncoso, M. Carmen Garcia-Parrilla
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Nutrients
Subjects:
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Online Access:https://www.mdpi.com/2072-6643/11/10/2421