Ectopic γ-catenin expression partially mimics the effects of stabilized β-catenin on embryonic stem cell differentiation.

Ectopic γ-catenin expression partially mimics the effects of stabilized β-catenin on embryonic stem cell differentiation.

β-catenin, an adherens junction component and key Wnt pathway effector, regulates numerous developmental processes and supports embryonic stem cell (ESC) pluripotency in specific contexts. The β-catenin homologue γ-catenin (also known as Plakoglobin) is a constituent of desmosomes and adherens junct...

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Bibliographic Details
Main Authors: Sujeivan Mahendram, Kevin F Kelly, Sabrina Paez-Parent, Sharmeen Mahmood, Enio Polena, Austin J Cooney, Bradley W Doble
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3664634?pdf=render

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http://europepmc.org/articles/PMC3664634?pdf=render

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