Interferon lambda protects the female reproductive tract against Zika virus infection

Zika virus infections can cause devastating congenital birth defects but the underlying interactions with the host immune system are not well understood. Here, the authors examine the immune basis of vaginal protection and susceptibility to Zika viral infection, and identify a hormonal dependent rol...

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Bibliographic Details
Main Authors: Elizabeth A. Caine, Suzanne M. Scheaffer, Nitin Arora, Konstantin Zaitsev, Maxim N. Artyomov, Carolyn B. Coyne, Kelle H. Moley, Michael S. Diamond
Format: Article
Language:English
Published: Nature Publishing Group 2019-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-07993-2