CCR7 Sulfotyrosine Enhances CCL21 Binding

CCR7 Sulfotyrosine Enhances CCL21 Binding

Chemokines are secreted proteins that direct the migration of immune cells and are involved in numerous disease states. For example, CCL21 (CC chemokine ligand 21) and CCL19 (CC chemokine ligand 19) recruit antigen-presenting dendritic cells and naïve T-cells to the lymph nodes and are thought to pl...

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Bibliographic Details
Main Authors: Andrew J. Phillips, Deni Taleski, Chad A. Koplinski, Anthony E. Getschman, Natasha A. Moussouras, Amanda M. Richard, Francis C. Peterson, Michael B. Dwinell, Brian F. Volkman, Richard J. Payne, Christopher T. Veldkamp
Format: Article
Language:English
Published: MDPI AG 2017-08-01
Series:International Journal of Molecular Sciences
Subjects:
chemokines
chemokine receptors
NMR
sulfotyrosine
CCL21
CCL19
CCR7
cancer metastasis
posttranslational modification
Online Access:https://www.mdpi.com/1422-0067/18/9/1857

Internet

https://www.mdpi.com/1422-0067/18/9/1857

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