Associations of ATR and CHEK1 single nucleotide polymorphisms with breast cancer.

DNA damage and replication checkpoints mediated by the ATR-CHEK1 pathway are key to the maintenance of genome stability, and both ATR and CHEK1 have been proposed as potential breast cancer susceptibility genes. Many novel variants recently identified by the large resequencing projects have not yet...

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Bibliographic Details
Main Authors: Wei-Yu Lin, Ian W Brock, Dan Connley, Helen Cramp, Rachel Tucker, Jon Slate, Malcolm W R Reed, Sabapathy P Balasubramanian, Lisa A Cannon-Albright, Nicola J Camp, Angela Cox
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3700940?pdf=render