Upregulation of Intestinal Barrier Function in Mice with DSS-Induced Colitis by a Defined Bacterial Consortium Is Associated with Expansion of IL-17A Producing Gamma Delta T Cells

Upregulation of Intestinal Barrier Function in Mice with DSS-Induced Colitis by a Defined Bacterial Consortium Is Associated with Expansion of IL-17A Producing Gamma Delta T Cells

Bacterial consortium transplantation (BCT) is a promising alternative to fecal microbiota transplantation in treating inflammatory bowel disease (IBD). Here, we showed that a defined bacterial consortium derived from healthy mice was able to enhance the intestinal barrier function of mice with dextr...

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Bibliographic Details
Main Authors: Ming Li, Bing Wang, Xiaotong Sun, Yan Tang, Xiaoqing Wei, Biying Ge, Yawei Tang, Ying Deng, Chunyang He, Jieli Yuan, Xia Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-07-01
Series:Frontiers in Immunology
Subjects:
inflammatory bowel disease
dysbiosis
bacterial consortium transplantation
γδT cells
IL-17A
occludin
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.00824/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.00824/full

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