NMR spectroscopy of macrophages loaded with native, oxidized or enzymatically degraded lipoproteins.

Oxidized and enzymatically modified low-density lipoproteins (oxLDL and eLDL) play a key role in early stages of atherogenesis. Their uptake by recruited macrophages leads to endolysosomal phospholipidosis or foam cell formation, respectively, each of which is preceded by highly differential lipid r...

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Bibliographic Details
Main Authors: Paul Ramm Sander, Markus Peer, Margot Grandl, Ulrich Bogdahn, Gerd Schmitz, Hans Robert Kalbitzer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3574142?pdf=render