Retinoic Acid Is Sufficient for the In Vitro Induction of Mouse Spermatocytes

Retinoic Acid Is Sufficient for the In Vitro Induction of Mouse Spermatocytes

Meiosis is the key step in gametogenesis. However, the mechanism of mammalian meiosis remains poorly understood due to the lack of an in vitro model. Here, we report that retinoic acid (RA) is sufficient for inducing leptotene/zygotene spermatocytes from cultured mouse spermatogonial stem cells. Mul...

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Bibliographic Details
Main Authors: Si Wang, Xiuxia Wang, Longfei Ma, Xiwen Lin, Daoqin Zhang, Zhen Li, Yujian Wu, Chunwei Zheng, Xue Feng, Shangying Liao, Yanmin Feng, Jian Chen, Xiangjing Hu, Min Wang, Chunsheng Han
Format: Article
Language:English
Published: Elsevier 2016-07-01
Series:Stem Cell Reports
Subjects:
spermatogonial stem cells
spermatocytes
Sertoli cells
meiosis
retinoic acid
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671116300686

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http://www.sciencedirect.com/science/article/pii/S2213671116300686

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