Clinical Relevance of Plasma Endogenous Tissue-Plasminogen Activator and Aortic Valve Sclerosis: Performance as a Diagnostic Biomarker

Clinical Relevance of Plasma Endogenous Tissue-Plasminogen Activator and Aortic Valve Sclerosis: Performance as a Diagnostic Biomarker

Background: Aortic valve sclerosis (AVSc), a common precursor to calcific aortic valve disease, may progress into advanced aortic stenosis with hemodynamic instability. However, plasma biomarkers of such a subclinical condition remain lacking. Since impaired fibrinolysis featuring dysregulated tissu...

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Bibliographic Details
Main Authors: Zhongli Chen, Ying Shen, Qiqi Xue, Bo Wen Lin, Xiao Yan He, Yi Bo Zhang, Ying Yang, Wei Feng Shen, Ye Hong Liu, Ke Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
calcific aortic valve disease
aortic valve sclerosis
tissue plasminogen activator
diagnostic value
biomarker
Online Access:https://www.frontiersin.org/article/10.3389/fcvm.2020.584998/full

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https://www.frontiersin.org/article/10.3389/fcvm.2020.584998/full

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