Pertussis Vaccine Candidate Based on Outer Membrane Vesicles Derived From Biofilm Culture

Pertussis Vaccine Candidate Based on Outer Membrane Vesicles Derived From Biofilm Culture

Outer membrane vesicles (OMV) derived from Bordetella pertussis—the etiologic agent of the resurgent disease called pertussis—are safe and effective in preventing bacterial colonization in the lungs of immunized mice. Vaccine formulations containing those OMV are capable of inducing a mixed Th1/Th2/...

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Bibliographic Details
Main Authors: Francisco Carriquiriborde, Pablo Martin Aispuro, Nicolás Ambrosis, Eugenia Zurita, Daniela Bottero, María Emilia Gaillard, Celina Castuma, Erika Rudi, Aníbal Lodeiro, Daniela F. Hozbor
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Immunology
Subjects:
Bordetella pertussis
outer membrane vesicles
biofilm
planktonic
protection
vaccine
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.730434/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.730434/full

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