In Mitochondria β-Actin Regulates mtDNA Transcription and Is Required for Mitochondrial Quality Control

Summary: In eukaryotic cells, actin regulates both cytoplasmic and nuclear functions. However, whether actin-based structures are present in the mitochondria and are involved in mitochondrial functions has not been investigated. Here, using wild-type β-actin +/+ and knockout (KO) β-actin −/− mouse e...

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Bibliographic Details
Main Authors: Xin Xie, Tomas Venit, Nizar Drou, Piergiorgio Percipalle
Format: Article
Language:English
Published: Elsevier 2018-05-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004218300531