Cumulative contact frequency of a chromatin region is an intrinsic property linked to its function

Regulation of gene transcription is a complex process controlled by many factors, including the conformation of chromatin in the nucleus. Insights into chromatin conformation on both local and global scales can be provided by the Hi-C (high-throughput chromosomes conformation capture) method. One of...

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Bibliographic Details
Main Authors: Margarita D. Samborskaia, Aleksandra Galitsyna, Ilya Pletenev, Anna Trofimova, Andrey A. Mironov, Mikhail S. Gelfand, Ekaterina E. Khrameeva
Format: Article
Language:English
Published: PeerJ Inc. 2020-08-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/9566.pdf