Niacinamide and undenatured type II collagen modulates the inflammatory response in rats with monoiodoacetate-induced osteoarthritis

Abstract The current work aimed to examine the properties of oral supplementation of niacinamide and undenatured type II collagen (UCII) on the inflammation and joint pain behavior of rats with osteoarthritis (OA). Forty-nine Wistar rats were allocated into seven groups; control (no MIA), MIA as a n...

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Bibliographic Details
Main Authors: Kazim Sahin, Osman Kucuk, Cemal Orhan, Mehmet Tuzcu, Ali Said Durmus, Ibrahim Hanifi Ozercan, Nurhan Sahin, Vijaya Juturu
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-94142-3