Species-Specific Conservation of Linear Antigenic Sites on Vaccinia Virus A27 Protein Homologs of Orthopoxviruses

Species-Specific Conservation of Linear Antigenic Sites on Vaccinia Virus A27 Protein Homologs of Orthopoxviruses

The vaccinia virus (VACV) A27 protein and its homologs, which are found in a large number of members of the genus <i>Orthopoxvirus</i> (OPXV), are targets of viral neutralization by host antibodies. We have mapped six binding sites (epitopes #1A: aa 32–39, #1B: aa 28–33, #1C: aa 26–31, #...

Full description

Bibliographic Details
Main Authors: Henrike P. Ahsendorf, Li L. Gan, Kamal H. Eltom, Ahmed Abd El Wahed, Sven-Kevin Hotop, Rachel L. Roper, Ulrike Beutling, Mark Broenstrup, Christiane Stahl-Hennig, Ludwig E. Hoelzle, Claus-Peter Czerny
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Viruses
Subjects:
Vaccinia virus A27 protein homologs
epitope mapping
phylogenetic epitope variation
neutralizing antibodies
Online Access:https://www.mdpi.com/1999-4915/11/6/493

Internet

https://www.mdpi.com/1999-4915/11/6/493

Similar Items