F-actin Regulates Osteoblastic Differentiation of Mesenchymal Stem Cells on TiO2 Nanotubes Through MKL1 and YAP/TAZ

F-actin Regulates Osteoblastic Differentiation of Mesenchymal Stem Cells on TiO2 Nanotubes Through MKL1 and YAP/TAZ

Abstract Titanium and titanium alloys are widely used in orthopedic implants. Modifying the nanotopography provides a new strategy to improve osseointegration of titanium substrates. Filamentous actin (F-actin) polymerization, as a mechanical loading structure, is generally considered to be involved...

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Bibliographic Details
Main Authors: Zhicheng Tong, Yanchang Liu, Runzhi Xia, Yongyun Chang, Yi Hu, Pengcheng Liu, Zanjing Zhai, Jingwei Zhang, Huiwu Li
Format: Article
Language:English
Published: SpringerOpen 2020-09-01
Series:Nanoscale Research Letters
Subjects:
TiO2 nanotubes
MSCs
Osteogenic differentiation
F-actin
MKL1
YAP/TAZ
Online Access:http://link.springer.com/article/10.1186/s11671-020-03415-9

Internet

http://link.springer.com/article/10.1186/s11671-020-03415-9

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