Development of a unique small molecule modulator of CXCR4.

Development of a unique small molecule modulator of CXCR4.

Metastasis, the spread and growth of tumor cells to distant organ sites, represents the most devastating attribute and plays a major role in the morbidity and mortality of cancer. Inflammation is crucial for malignant tumor transformation and survival. Thus, blocking inflammation is expected to serv...

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Bibliographic Details
Main Authors: Zhongxing Liang, Weiqiang Zhan, Aizhi Zhu, Younghyoun Yoon, Songbai Lin, Maiko Sasaki, Jan-Michael A Klapproth, Hua Yang, Hans E Grossniklaus, Jianguo Xu, Mauricio Rojas, Ronald J Voll, Mark M Goodman, Richard F Arrendale, Jin Liu, C Chris Yun, James P Snyder, Dennis C Liotta, Hyunsuk Shim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3317778?pdf=render

Internet

http://europepmc.org/articles/PMC3317778?pdf=render

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